Hydrofluoric Acid → 2-Fluoro-m-xylene
반응식
FC(O[C:5]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:6]=1[CH3:12])=O.[FH:13]>>[CH3:12][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]([CH3:11])[C:5]=1[F:13]참가 물질
3
반응 조건
- 온도
- 140 °C
실험 절차
200 ml of anhydrous hydrogen fluoride were placed at 0° C. in a stainless steel laboratory autoclave and 100 g of 2,6-dimethylphenyl fluoroformate were added dropwise. The autoclave was sealed and heated at a maximum temperature of 140° C. for 1.5 hours. The reaction mixture was worked up as described in Example 9. 2,6-Dimethylfluorobenzene was obtained in a yield of 75%.
후처리
- additionwere added dropwise
- customThe autoclave was sealed
출처 및 근거
- ORD 기록
- ord-0378ee7987964b1e8d46c22a9b389338
- 출처 데이터셋
- uspto-grants-1994_04
- 특허 번호
- US05306849
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