Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → [3-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Chloroacetone | HCID 6571 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 2-(3-Mercaptophenyl)acetic acid | HCID 3543156 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | [3-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid | HCID 66765032 | — |
반응 단계
3-Mercaptophenylacetic acid (3.0 g, 17.9 mmol) and chloroacetone (1.5 mL, 18.8 mmol) were combined in THF (100 mL) then a solution of N,N-diisopropylethylamine (10.9 mL, 62.7 mmol) in THF (100 mL) was added by addition funnel over the course of 20 minutes at room temperature. After 2 hours H2O (100 mL) was added and the reaction mixture was worked up to give the title compound as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09000025B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-43f2b3ce0f734867bc89fec3f9b9d4f8 |
| 출처 메모 | uspto-grants-2015_04 |