Ethanol → 3-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

HRID 1466821노트

반응식

HRID 1466821 반응식
[O:1]=[C:2]([CH3:14])[CH2:3][S:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9].OS(O)(=O)=O.[CH2:20](O)[CH3:21]>>[CH2:20]([O:9][C:8](=[O:10])[C:7]1[CH:11]=[CH:12][CH:13]=[C:5]([S:4][CH2:3][C:2](=[O:1])[CH3:14])[CH:6]=1)[CH3:21]

참가 물질

4

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 667650833-(2-Oxo-propylsulfanyl)-benzoic acid

생성물 1

HCID 667651013-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

실험 절차

3-(2-Oxo-propylsulfanyl)-benzoic acid from the previous reaction was dissolved in ethanol and a catalytic amount of conc. H2SO4 was added. The reaction was monitored by analytical TLC and when it was complete the reaction was concentrated to dryness and the resulting residue was purified via silica gel chromatography to give the title compound.

후처리

  1. concentrationwas concentrated to dryness
  2. customthe resulting residue was purified via silica gel chromatography

출처 및 근거

ORD 기록
ord-9d8e3d678b22485cadca128bc1209fc9
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09000025B2

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