(3-Chloro-2-fluorophenyl)hydrazine hydrochloride → 3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

HRID 1466908노트

반응식

HRID 1466908 반응식
[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][CH2:12][C:13](=O)[CH3:14])[CH:6]=1)[CH3:2].Cl.[Cl:18][C:19]1[C:20]([F:27])=[C:21]([NH:25]N)[CH:22]=[CH:23][CH:24]=1>>[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:22]3[C:21](=[C:20]([F:27])[C:19]([Cl:18])=[CH:24][CH:23]=3)[NH:25][C:13]=2[CH3:14])[CH:6]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 25067375(3-Chloro-2-fluorophenyl)hydrazine hydrochlorideHCID 667651013-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

생성물 1

HCID 667655043-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

실험 절차

Prepared according to the procedure described in Example 2, step 1, using the following starting materials: 3-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester and (3-Chloro-2-fluoro-phenyl)-hydrazine hydrochloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-12f27756651c42ce87eaf9e98116a5a8
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09000025B2

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