4-Bromo-1-ethyl-1H-pyrazole → 3-[6-cyano-1-(1-ethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid methyl ester

HRID 1466931

반응식

HRID 1466931 반응식
[CH3:1][O:2][C:3](=[O:23])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([C:20]#[N:21])=[CH:17][CH:18]=3)[NH:13][C:12]=2[CH3:22])[CH:5]=1.Br[C:25]1[CH:26]=[N:27][N:28]([CH2:30][CH3:31])[CH:29]=1>>[CH3:1][O:2][C:3](=[O:23])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([C:20]#[N:21])=[CH:17][CH:18]=3)[N:13]([C:25]3[CH:26]=[N:27][N:28]([CH2:30][CH3:31])[CH:29]=3)[C:12]=2[CH3:22])[CH:5]=1

참가 물질

3

반응물 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 667650153-(6-Cyano-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester

생성물 1

HCID 667655773-[6-cyano-1-(1-ethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid methyl ester

실험 절차

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-cyano-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester and 4-bromo-1-ethyl-1H-pyrazole.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-f07037cd6670417185c8f0058e75ddf4
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09000025B2

연결된 노트

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