1-(cyclopropylmethyl)-4-iodo-1H-pyrazole → 3-[6-Chloro-1-(1-cyclopropylmethyl-1H-pyrazol-4-yl)-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester
반응식
[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[NH:14][C:13]=2[CH3:23])[CH:6]=1)[CH3:2].[CH:25]1([CH2:28][N:29]2[CH:33]=[C:32](I)[CH:31]=[N:30]2)[CH2:27][CH2:26]1>>[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[N:14]([C:32]3[CH:31]=[N:30][N:29]([CH2:28][CH:25]4[CH2:27][CH2:26]4)[CH:33]=3)[C:13]=2[CH3:23])[CH:6]=1)[CH3:2]참가 물질
3
실험 절차
Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 1-cyclopropylmethyl-4-iodo-1H-pyrazole.
후처리
- customPrepared