5-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine → HCID 66746982, 화합물

HRID 1467066

반응식

HRID 1467066 반응식
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][C:14]([CH3:19])([CH3:18])[C:15]([OH:17])=O)[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22].[CH3:26][O:27][C:28]1[CH:37]=[CH:36][CH:35]=[C:34]2[C:29]=1[CH2:30][CH2:31][CH2:32][CH:33]2[NH2:38]>>[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][C:14]([CH3:18])([CH3:19])[C:15]([NH:38][CH:33]2[C:34]3[C:29](=[C:28]([O:27][CH3:26])[CH:37]=[CH:36][CH:35]=3)[CH2:30][CH2:31][CH2:32]2)=[O:17])[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22]

참가 물질

3

반응물 2

HCID 388995-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amineHCID 667468783-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid

생성물 1

HCID 66746982HCID 66746982, 화합물

실험 절차

Prepared as in Example 24a from 3-((4-amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid (Example 47b) and 5-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine as a brown solid (40%). MS 506 (MH+).

출처 및 근거

ORD 기록
ord-6757fad24408403b88df9c16242bb5b8
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09000054B2

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