Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(2-Hydroxyethoxy)-3-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(2-Hydroxyethoxy)-3-methoxybenzoic acid | HCID 24694069 | — |
| 반응물 | (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylate | HCID 86658188 | — |
| 생성물 | (S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate | HCID 86658194 | — |
반응 단계
Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methyl-quinoline-3-carboxylate (Example 26b) and 4-(2-hydroxyethoxy)-3-methoxybenzoic acid (Uto, Y. et al. Bioorg. Med. Chem. Lett. 2009, 19, 4151.) as a brown solid. MS 498 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09000054B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-9e9c9ba88599423a9679b06f78ade9cf |
| 출처 메모 | uspto-grants-2015_04 |