Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(2-Hydroxyethoxy)-3-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)butoxy)-2-methylquinoline-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(2-Hydroxyethoxy)-3-methoxybenzoic acid | HCID 24694069 | — |
| 반응물 | (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate | HCID 86658218 | — |
| 생성물 | (S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)butoxy)-2-methylquinoline-3-carboxylate | HCID 86658220 | — |
반응 단계
Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate (Example 97b) and 4-(2-hydroxyethoxy)-3-methoxybenzoic acid (Uto, Y. et al. Bioorg. Med. Chem. Lett. 2009, 19, 4151.) as brown solid (38%). MS 512 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09000054B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-b76ab25913c4475584ba9be9c0d95259 |
| 출처 메모 | uspto-grants-2015_04 |