1-(2-Hydroxyethyl)-1H-pyrazole → 2-(2-(1H-pyrazol-1-yl)ethoxy)-6-nitrobenzonitrile

반응식

[N:1]1([CH2:6][CH2:7][OH:8])[CH:5]=[CH:4][CH:3]=[N:2]1.[N+:9]([C:12]1[CH:19]=[CH:18][CH:17]=[C:16]([N+]([O-])=O)[C:13]=1[C:14]#[N:15])([O-:11])=[O:10]>>[N:1]1([CH2:6][CH2:7][O:8][C:16]2[CH:17]=[CH:18][CH:19]=[C:12]([N+:9]([O-:11])=[O:10])[C:13]=2[C:14]#[N:15])[CH:5]=[CH:4][CH:3]=[N:2]1

참가 물질

반응물 2

HCID 2370311-(2-Hydroxyethyl)-1H-pyrazole

HCID 520718Dinitrobenzonitrile

생성물 1

HCID 667472142-(2-(1H-pyrazol-1-yl)ethoxy)-6-nitrobenzonitrile수율 89.2%

실험 절차

Prepared as in Example 197197c from 2-(1H-pyrazol-1-yl)ethanol and 2,6-dinitrobenzonitrile in 89.2% yield. MS 259 (MH+).

출처 및 근거

ORD 기록: ord-e415b2622bc54870a439a170adcb9c68
출처 데이터셋: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09000054B2

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