2,4-Dibromo-1,3-thiazole → HCID 67608573, 화합물

반응식

[CH2:1]([C:3]1[N:4]=[CH:5][C:6]([N:9]2[CH2:14][CH2:13][CH:12]([OH:15])[CH2:11][CH2:10]2)=[N:7][CH:8]=1)[CH3:2].Br[C:17]1[S:18][CH:19]=[C:20]([Br:22])[N:21]=1>>[Br:22][C:20]1[N:21]=[C:17]([O:15][CH:12]2[CH2:13][CH2:14][N:9]([C:6]3[CH:5]=[N:4][C:3]([CH2:1][CH3:2])=[CH:8][N:7]=3)[CH2:10][CH2:11]2)[S:18][CH:19]=1

참가 물질

반응물 2

HCID 27632972,4-Dibromo-1,3-thiazole

HCID 67608386HCID 67608386, 화합물

생성물 1

HCID 67608573HCID 67608573, 화합물

실험 절차

The title compound was prepared by following the similar procedure as described in Intermediate-42 using 1-(5-ethylpyrazin-2-yl)piperidin-4-ol and 2,4-dibromothiazole (0.480 g, 54%); MS: 369.2 (M+1).

출처 및 근거

ORD 기록: ord-aeff33fc91744390aed4c139eb2cd541
출처 데이터셋: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09000175B2

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