5-(Methylsulfonyl)-1H-indole → tert-butyl 4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)oxy)piperidine-1-carboxylate

반응식

Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O-:17])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[CH3:18][S:19]([C:22]1[CH:23]=[C:24]2[C:28](=[CH:29][CH:30]=1)[NH:27][CH:26]=[CH:25]2)(=[O:21])=[O:20].[CH3:31][C:32]([O-])([CH3:34])[CH3:33].[Na+]>O1CCOCC1.CC(O)=O.CC(P(C(C)(C)C)C1C(C2[C-]=CC=CC=2)=CC=CC=1)(C)C.[Pd]>[CH3:18][S:19]([C:22]1[CH:23]=[C:24]2[C:28](=[CH:29][CH:30]=1)[N:27]([C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]3[CH2:14][CH2:13][N:12]([C:15]([O:17][C:32]([CH3:34])([CH3:33])[CH3:31])=[O:16])[CH2:11][CH2:10]3)=[CH:4][CH:3]=1)[CH:26]=[CH:25]2)(=[O:21])=[O:20]