N,N-dimethyl-1H-indole-5-carboxamide → tert-butyl 4-(((6-(5-(dimethylcarbamoyl)-1H-indol-1-yl)pyridin-3-yl)oxy) methyl)piperidine-1-carboxylate
반응식
[CH3:1][N:2]([CH3:14])[C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][CH:9]=[CH:8]2)=[O:4].[C:15]([O:19][C:20]([N:22]1[CH2:27][CH2:26][CH:25]([CH2:28][O:29][C:30]2[CH:31]=[N:32][C:33](Cl)=[CH:34][CH:35]=2)[CH2:24][CH2:23]1)=[O:21])([CH3:18])([CH3:17])[CH3:16]>>[CH3:1][N:2]([CH3:14])[C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:33]1[N:32]=[CH:31][C:30]([O:29][CH2:28][CH:25]3[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:21])[CH2:27][CH2:26]3)=[CH:35][CH:34]=1)[CH:9]=[CH:8]2)=[O:4]참가 물질
3
실험 절차
The title compound was prepared by following the similar procedure as described in Example-1 by using N,N-dimethyl-1H-indole-5-carboxamide (intermediate-12) and tert-butyl-4-(((6-chloropyridin-3-yl)oxy)methyl)piperidine-1-carboxylate (Intermediate 29).
출처 및 근거
- ORD 기록
- ord-10756cd892af4d799ca37ef89e6b5ff5
- 출처 데이터셋