Cyclopropylamine → HCID 66747793, 화합물

HRID 1469070노트

반응식

HRID 1469070 반응식
[C:1]1([CH3:28])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[N:13]=[C:12]([N:17]1[CH:21]=[C:20]([C:22]([O:24]CC)=[O:23])[CH:19]=[N:18]1)[NH:11][C:10]2=O.[CH:29]1([NH2:32])[CH2:31][CH2:30]1>>[CH:29]1([NH:32][C:10]2[C:9]3[C:14](=[CH:15][CH:16]=[C:7]([C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=4[CH3:28])[CH:8]=3)[N:13]=[C:12]([N:17]3[CH:21]=[C:20]([C:22]([OH:24])=[O:23])[CH:19]=[N:18]3)[N:11]=2)[CH2:31][CH2:30]1

참가 물질

3

반응물 2

HCID 69828CyclopropylamineHCID 136337162HCID 136337162, 화합물

생성물 1

HCID 66747793HCID 66747793, 화합물

실험 절차

The above compound may be made analogous to Example 1 using ethyl 1-(6-(o-tolyl)-4-oxo-3,4-dihydroquinazolin-2-yl)-1H-pyrazole-4-carboxylate in step D and cyclopropylamine in step E. MS (ESI/CI): predicted mass C22H19N5O2, 385.2.

출처 및 근거

ORD 기록
ord-8626caa144954a43a1da820e64ede3d5
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09006251B2

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