Sodium Carbonate → 1,4-Benzenedicarboxaldehyde, 2,5-dihydroxy-

HRID 1471325노트

반응식

HRID 1471325 반응식
C[O:2][C:3]1[CH:8]=[C:7]([CH:9]=[O:10])[C:6]([O:11]C)=[CH:5][C:4]=1[CH:13]=[O:14].B(Br)(Br)Br.C(=O)([O-])[O-].[Na+].[Na+]>ClC1C=CC=CC=1>[OH:2][C:3]1[CH:8]=[C:7]([CH:9]=[O:10])[C:6]([OH:11])=[CH:5][C:4]=1[CH:13]=[O:14]

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 25134Boron tribromideHCID 6066482,5-Dimethoxyterephthalaldehyde

생성물 1

HCID 110842361,4-Benzenedicarboxaldehyde, 2,5-dihydroxy-

시약·촉매·용매 1

HCID 7964Chlorobenzene용매

실험 절차

0.5 g of 2,5-dimethoxybenzene-1,4-dicarboaldehyde (AD) and 25 mL of boron tribromide were dissolved in 150 mL of chlorobenzene and stirred at room temperature for 12 hours. After complete reaction, the reacted mixture was neutralized with sodium carbonate, followed by extraction with water and dichloromethane and recrystallization within dichloromethane, thereby obtaining 2,5-dihydroxybenzene-1,4-dicarboaldehyde. The obtained product exhibited yield, property and NMR analysis result as follows.

후처리

  1. customAfter complete reaction
  2. extractionfollowed by extraction with water and dichloromethane and recrystallization within dichloromethane
  3. customThe obtained product exhibited yield
  4. customproperty and NMR analysis result

출처 및 근거

ORD 기록
ord-a7cccfe99d784838bf2079719d6825a5
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09012230B2

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