Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(N-Ethylaminocarbonyl)phenylboronic acid → 4-[5-(4-Ethylcarbamoyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(N-Ethylaminocarbonyl)phenylboronic acid | HCID 3411307 | — |
| 반응물 | 4-(5-Chlorofuro[2,3-c]pyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester | HCID 86674889 | — |
| 생성물 | 4-[5-(4-Ethylcarbamoyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 71736416 | — |
반응 단계
The title compound is prepared from 4-(5-chloro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester and 4-ethylcarbamoyl-phenylboronic acid following a procedure analogous to that described for Example 1; the reaction is conducted at 150° C. LC (method 4): tR=1.68 min; Mass spectrum (ESI+): m/z=450 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09012456B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-84755c5c51e145e583c4e8701482eec7 |
| 출처 메모 | uspto-grants-2015_04 |