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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1471841생성일: 2026년 10월 25일

4-(4-Methylpiperazine-1-carbonyl)phenylboronic acid → 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(4-(4-methylpiperazine-1-carbonyl)phenyl)isoquinolin-3-yl)cyclopropanecarboxamide

https://huagongshe.com/reaction/1471841

반응식

참여 물질

역할이름HCID투입량
반응물4-(4-Methylpiperazine-1-carbonyl)phenylboronic acidHCID 12993042—
반응물N-(1-Bromoisoquinolin-3-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamideHCID 57732996—
반응물2,2-difluorobenzo[d][1,3]dioxol-5-yl-N-(1-phenylisoquinolin-3-yl)cyclopropanecarboxamideHCID 57733001—
생성물1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(4-(4-methylpiperazine-1-carbonyl)phenyl)isoquinolin-3-yl)cyclopropanecarboxamideHCID 57733022—

반응 단계

1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-phenylisoquinolin-3-yl)cyclopropanecarboxamide was made by the procedure shown above starting from N-(1-bromoisoquinolin-3-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide and 4-(4-methylpiperazine-1-carbonyl)phenylboronic acid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09012473B2
출처 데이터셋uspto-grants-2015_04
ORD IDord-0dbff496d83d4363b4bfae3833bc212c
출처 메모uspto-grants-2015_04