5-Amino-6,7-difluoro-1-(2-fluorocyclopropyl)-8-methoxy-4-oxoquinoline-3-carboxylic acid → 5-Amino-7-[3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-8-methoxy-4-oxoquinoline-3-carboxylic acid

HRID 147352

반응식

HRID 147352 반응식
[CH:24]1([NH:27][CH2:28][CH:29]2[CH2:30][NH:31][CH2:32][CH:33]2[F:34])[CH2:25][CH2:26]1.[NH2:1][c:2]1[c:3]2[c:4](=[O:23])[c:5]([C:20](=[O:21])[OH:22])[cH:6][n:7]([CH:16]3[CH:17]([F:19])[CH2:18]3)[c:8]2[c:9]([O:14][CH3:15])[c:10]([F:13])[c:11]1[F:12]>>[NH2:1][c:2]1[c:3]2[c:4](=[O:23])[c:5]([C:20](=[O:21])[OH:22])[cH:6][n:7]([CH:16]3[CH:17]([F:19])[CH2:18]3)[c:8]2[c:9]([O:14][CH3:15])[c:10]([N:31]2[CH2:30][CH:29]([CH2:28][NH:27][CH:24]3[CH2:25][CH2:26]3)[CH:33]([F:34])[CH2:32]2)[c:11]1[F:12]

참가 물질

3

반응물 2

HCID 212610175-Amino-6,7-difluoro-1-(2-fluorocyclopropyl)-8-methoxy-4-oxoquinoline-3-carboxylic acidHCID 230620733-Pyrrolidinemethanamine,N-cyclopropyl-4-fluoro-,(3R,4S)-(9CI)

생성물 1

HCID 231256485-Amino-7-[3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-8-methoxy-4-oxoquinoline-3-carboxylic acid

출처 및 근거

ORD 기록
ord-187df1f9a8d240b3bbcd9611438384be
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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