Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tyramine → 4-{2-[4-(3-Nitro-phenyl)-pyrimidin-2-ylamino]-ethyl}-phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tyramine | HCID 5610 | — |
| 반응물 | 2-Chloro-4-(3-nitrophenyl)pyrimidine | HCID 24901887 | — |
| 생성물 | 4-{2-[4-(3-Nitro-phenyl)-pyrimidin-2-ylamino]-ethyl}-phenol | HCID 58603596 | — |
반응 단계
Intermediate 5 was coupled with tyramine following procedure F. LC-MS showed the product had the expected M+H+ of 337. 1H NMR (Varian 300 MHz, DMSO-d6, shifts relative to the solvent peak at 2.49 ppm) (d, 1H) 7.6-6.6 (m, 7H) 6.0 (d, 2H) 4.85 (s, 2H) 4.40 (d, 2H) 3.0 (m, 1H), 2.0 (m, 4H), 1.6 (m, 4H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732444B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-4e4ba4184bf14a818288b76f29c1c248 |
| 출처 메모 | uspto-grants-2010_06 |