Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 4-Benzyloxy-2-methoxyphenylacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Tert-butyl 2-(4-benzyloxy-2-methoxyphenyl)acetate | HCID 67304738 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-Benzyloxy-2-methoxyphenylacetic acid | HCID 11065571 | — |
반응 단계
A solution of tert-butyl [4-(benzyloxy)-2-methoxyphenyl]acetate (2.2 g, 6.70 mmol) in DCM (10 ml) was treated with TFA (10.3 ml, 134 mmol) and the mixture stirred at RT for 30 min. The volatiles were removed in vacuo to afford the title compound. LC/MS (m/z): 273 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09018224B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-b4e56eec541d44e08e7620453b45efec |
| 출처 메모 | uspto-grants-2015_04 |