N-Methoxy-N-methylacetamide → 6-Acetyl-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester

HRID 1475496노트

반응식

HRID 1475496 반응식
[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[N:12][CH:13]=[C:14](Br)[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].CON(C)[C:23](=[O:25])[CH3:24]>>[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[N:12][CH:13]=[C:14]([C:23](=[O:25])[CH3:24])[CH:15]=2)[C:10]([CH3:19])([CH3:18])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 537505N-Methoxy-N-methylacetamideHCID 70980192HCID 70980192, 화합물

생성물 1

HCID 709807126-Acetyl-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester

실험 절차

Prepared from 6-bromo-3,3-dimethyl-2,3-dihydro-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester and N-methoxy-N-methyl-acetamide using a procedure analogous to that of Preparation 263. MS: [M+H]+=291.

후처리

  1. customof Preparation 263

출처 및 근거

ORD 기록
ord-889aa4648b4844c7a5fafec1e2729512
출처 데이터셋
uspto-grants-2015_04
특허 번호
US09018214B2

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