Methyl 1-aminocycloheptane-1-carboxylate hydrochloride → 1-{[7-(2-m-Tolyl-ethoxy)-benzo[1,3]dioxole-5-carbonyl]-amino}-cycloheptanecarboxylic Acid Methyl Ester
반응식
[C:1]1([CH3:22])[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][O:9][C:10]2[C:15]3[O:16][CH2:17][O:18][C:14]=3[CH:13]=[C:12]([C:19]([OH:21])=O)[CH:11]=2)[CH:2]=1.Cl.[CH3:24][O:25][C:26]([C:28]1([NH2:35])[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1)=[O:27]>>[CH3:24][O:25][C:26]([C:28]1([NH:35][C:19]([C:12]2[CH:11]=[C:10]([O:9][CH2:8][CH2:7][C:3]3[CH:2]=[C:1]([CH3:22])[CH:6]=[CH:5][CH:4]=3)[C:15]3[O:16][CH2:17][O:18][C:14]=3[CH:13]=2)=[O:21])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1)=[O:27]참가 물질
3
실험 절차
The title compound was synthesized from 7-(2-m-tolyl-ethoxy)-benzo[1,3]dioxole-5-carboxylic acid and 1-amino-cycloheptanecarboxylic acid methyl ester hydrochloride in analogy to example 126, step 4.
출처 및 근거
- ORD 기록
- ord-f6550e4f8cb64121aa99ec71682e4753
- 출처 데이터셋
- uspto-grants-2015_04