1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → 6-(3,4-difluorophenyl)-3-[1-({4-[(4aR,10bR)-9-ethoxy-8-methoxy-3,4,4a,10b-tetrahydro-1H-thiopyrano[4,3-c]isoquinolin-6-yl]phenyl}carbonyl)piperidin-4-yl]-1-[(3-ethyl-1,2,4-oxadiazol-5-yl)methyl]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione

반응식

Cl.[F:2][C:3]1[CH:4]=[C:5]([C:10]2[S:18][C:17]3[C:16](=[O:19])[N:15]([CH:20]4[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]4)[C:14](=[O:26])[N:13]([CH2:27][C:28]4[O:32][N:31]=[C:30]([CH2:33][CH3:34])[N:29]=4)[C:12]=3[CH:11]=2)[CH:6]=[CH:7][C:8]=1[F:9].[CH2:35]([O:37][C:38]1[C:47]([O:48][CH3:49])=[CH:46][C:45]2[C:44]([C:50]3[CH:58]=[CH:57][C:53]([C:54](O)=[O:55])=[CH:52][CH:51]=3)=[N:43][C@@H:42]3[CH2:59][CH2:60][S:61][CH2:62][C@@H:41]3[C:40]=2[CH:39]=1)[CH3:36].C1C=CC2N(O)N=NC=2C=1.CCN=C=NCCCN(C)C>CN(C=O)C>[F:2][C:3]1[CH:4]=[C:5]([C:10]2[S:18][C:17]3[C:16](=[O:19])[N:15]([CH:20]4[CH2:21][CH2:22][N:23]([C:54]([C:53]5[CH:57]=[CH:58][C:50]([C:44]6[C:45]7[CH:46]=[C:47]([O:48][CH3:49])[C:38]([O:37][CH2:35][CH3:36])=[CH:39][C:40]=7[C@H:41]7[CH2:62][S:61][CH2:60][CH2:59][C@H:42]7[N:43]=6)=[CH:51][CH:52]=5)=[O:55])[CH2:24][CH2:25]4)[C:14](=[O:26])[N:13]([CH2:27][C:28]4[O:32][N:31]=[C:30]([CH2:33][CH3:34])[N:29]=4)[C:12]=3[CH:11]=2)[CH:6]=[CH:7][C:8]=1[F:9]