Ethylamine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-ethyl-amine

HRID 14775

반응식

HRID 14775 반응식
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH:11]=O)[CH:5]=[CH:4][N:3]=1.[CH2:16]([NH2:18])[CH3:17]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH2:11][NH:18][CH2:16][CH3:17])[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 6341EthylamineHCID 249019653-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

생성물 1

HCID 86603259[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-ethyl-amine

실험 절차

Intermediate 1 was coupled with ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 248.

출처 및 근거

ORD 기록
ord-1215636967b7414eb8c1f3c627a000b5
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07732444B2

연결된 노트

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