Thionyl Chloride → 6-(Chloromethyl)benzothiazole
반응식
[S:1]1[C:5]2[CH:6]=[C:7]([CH2:10]O)[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.S(Cl)([Cl:14])=O>ClCCl>[Cl:14][CH2:10][C:7]1[CH:8]=[CH:9][C:4]2[N:3]=[CH:2][S:1][C:5]=2[CH:6]=1참가 물질
4
실험 절차
To a dichloromethane solution (1.2 mL) of benzo[d]thiazol-6-yl-methanol (60 mg, 0.36 mmol), thionyl chloride (53 μL) was added at room temperature and the resultant solution was stirred for 1 day. After completion of the reaction, the reaction solution was concentrated under reduced pressure to obtain a crude product of the title compound.
후처리
- customAfter completion of the reaction
- concentrationthe reaction solution was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-85233e78dff84b6e92a6f70fdca9bdc8
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09403798B2
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