참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Amino-5-bromobenzoic acid | HCID 79858 | — |
| 반응물 | 1,1,1-Trifluoro-3-phenyl-2-propanone | HCID 222958 | — |
| 반응물 | Phosphorus Pentoxide-Methanesulfonic Acid | HCID 86584057 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178515323 | HCID 178515323 | — |
반응 단계
A mixture of 2-amino-5-bromobenzoic acid (3.01 g, 13.9 mmol), 1,1,1-trifluoro-3-phenylpropan-2-one (3.11 g, 16.5 mmol), and Eaton's reagent (9.3 mL) in a sealed tube was heated at 100° C. for 4 hours. The reaction mixture was then allowed to cool to room temperature, water was added slowly, and the mixture was stirred vigorously for about 15 minutes. The precipitated solid was collected by filtration, washed with water, and dried to provide the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09403816B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_08 |
|---|
| ORD ID | ord-172326b040a8495d908a15a67fd90a48 |
|---|
| 출처 메모 | uspto-grants-2016_08 |
|---|
