2-Chloro-4-(trifluoromethoxy)aniline → 1-(2-Chloro-4-(trifluoromethoxy)phenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

HRID 1478796노트

반응식

HRID 1478796 반응식
ClC1C=C(OC)C=CC=1N1[C:14]([CH3:15])=[C:13]([C:16]([OH:18])=[O:17])[N:12]=[N:11]1.[Cl:19][C:20]1[CH:26]=[C:25]([O:27][C:28]([F:31])([F:30])[F:29])[CH:24]=[CH:23][C:21]=1[NH2:22]>>[Cl:19][C:20]1[CH:26]=[C:25]([O:27][C:28]([F:29])([F:30])[F:31])[CH:24]=[CH:23][C:21]=1[N:22]1[C:14]([CH3:15])=[C:13]([C:16]([OH:18])=[O:17])[N:12]=[N:11]1

참가 물질

3

반응물 2

HCID 27340842-Chloro-4-(trifluoromethoxy)anilineHCID 836626001-(2-chloro-4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

생성물 1

HCID 1185132681-(2-Chloro-4-(trifluoromethoxy)phenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

실험 절차

The title compound was prepared analogously to 1-(2-chloro-4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (Example step 2) by replacing 2-chloro-4-methoxyaniline (step 1) with 2-chloro-4-trifluoromethoxyaniline.

출처 및 근거

ORD 기록
ord-1e3354a1c82344eeb194db71f54bf87c
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09403833B2

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