m-Chloroperbenzoic acid → HCID 59464117, 화합물

HRID 1478886노트

반응식

HRID 1478886 반응식
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:4][CH:3]=1.C1C=C(Cl)C=C(C(OO)=[O:21])C=1>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:6][N+:7]=1[O-:21]

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 53419528Methyl 2-(6-chloropyridin-3-yl)acetate

생성물 1

HCID 59464117HCID 59464117, 화합물수율 92.1%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To methyl 2-(6-chloropyridin-3-yl)acetate (2.5 g) in DCM (100 mL) was added mCPBA (4.6 g). The resulting reaction mixture was stirred at room temperature for 4 hr. The organic phase was washed with sat. NaHCO3, dried over Na2SO4, and concentrated. The crude product was purified by flash chromatography to afford the title product (2.5 g).

후처리

  1. customThe resulting reaction mixture
  2. washThe organic phase was washed with sat. NaHCO3
  3. dry with materialdried over Na2SO4
  4. concentrationconcentrated
  5. customThe crude product was purified by flash chromatography

출처 및 근거

ORD 기록
ord-b175f0a40b0348f3a7895e9696e78964
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09403850B2

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