Sodium Iodide → 3-Iodopropyl-tris(trimethylsiloxy)silane

HRID 1478938노트

반응식

HRID 1478938 반응식
Cl[CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8].[I-:21].[Na+]>CC(C)=O>[I:21][CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8]

참가 물질

4

반응물 2

HCID 5238Sodium IodideHCID 27578913-(3-Chloropropyl)-1,1,1,5,5,5-hexamethyl-3-((trimethylsilyl)oxy)trisiloxane

생성물 1

HCID 223256933-Iodopropyl-tris(trimethylsiloxy)silane수율 79.4%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

90 g of 3-chloropropyltris(trimethylsiloxy)silane (27) (Chem. Abstracts No. 18077-31-1) and 105.22 g of sodium iodide are added to 250 ml of acetone and stirred for 24 hours at reflux. The acetone is evaporated and the residue taken up in methylene chloride. The organic phase is washed with water, dried and evaporated. 89 g of the desired 3-iodopropyl-tris(trimethylsiloxy)silane (28) are obtained; 1H-NMR (ppm, CDCl3): 3.12 2H t, 1.75 2H txt, 0.43 2H t, 0 27H s.

후처리

  1. temperatureat reflux
  2. customThe acetone is evaporated
  3. washThe organic phase is washed with water
  4. customdried
  5. customevaporated

출처 및 근거

ORD 기록
ord-991fa046e4424002a203c0a700519931
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09403987B2

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