Ethyl trifluoroacetate → 12-Trifluoroacetamidododecanol
반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14].C([O:17][C:18](=O)[C:19]([F:22])([F:21])[F:20])C>C(O)C>[F:20][C:19]([F:22])([F:21])[C:18]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14])=[O:17]참가 물질
4
실험 절차
An ethanol solution (100 ml) of 12-aminododecanol (4.81 g, 23.9 mmol) and trifluoroacetic acid ethyl ester (6.79 g, 47.8 mmol) was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure to give 12-trifluoroacetamidododecanol (1) (6.98 g, q.) as a colorless syrup.
후처리
- concentrationThe reaction mixture was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-18304123fc9a41c1bd0a0ee8e098ed8f
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09404108B2
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