HCID 58455289, 화합물 → 1,3-Dihydroxypropan-2-yl phenyl succinate

HRID 1479231노트

반응식

HRID 1479231 반응식
[C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:19])[CH2:2][CH2:3][C:4]([O:6][CH:7]1[CH2:12][O:11]C(C2C=CC=CC=2)[O:9][CH2:8]1)=[O:5]>C(O)C.[Pd]>[C:4]([O:6][CH:7]([CH2:12][OH:11])[CH2:8][OH:9])(=[O:5])[CH2:3][CH2:2][C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]

참가 물질

4

반응물 1

HCID 58455289HCID 58455289, 화합물

생성물 1

HCID 584552561,3-Dihydroxypropan-2-yl phenyl succinate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

Phenyl 2-phenyl-1,3-dioxan-5-yl succinate (0.11 g, 0.3 mmol) was dissolved in ethanol (20 ml) under argon and Pd/C (0.09 g, 0.1 mmol) was added. The flask was flushed with hydrogen and allowed to stir under 1 atm H2 at room temperature for 16 h. The crude reaction mixture was passed through a plug of celite and the solvent was removed under reduced pressure yielding (0.9 g, 0.26 mmol, 89%). The product was used without any further purification.

후처리

  1. customThe flask was flushed with hydrogen
  2. customThe crude reaction mixture
  3. customthe solvent was removed under reduced pressure
  4. customyielding (0.9 g, 0.26 mmol, 89%)
  5. customThe product was used without any further purification

출처 및 근거

ORD 기록
ord-334dd724a2214bd7b923525dd7afdfd7
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09408919B2

반응 노트

불러오는 중…