3-Bromo-6-chloroimidazo(1,2-b)pyridazine → HCID 71491985, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:11]3[O:19][C:18]4[C:13](=NC=[CH:16][CH:17]=4)[CH:12]=3)=[CH:9][N:10]=2)[N:7]=1.BrC1N2N=C(Cl)C=CC2=[N:23][CH:22]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:11]3[O:19][C:18]4[CH:17]=[CH:16][N:23]=[CH:22][C:13]=4[CH:12]=3)=[CH:9][N:10]=2)[N:7]=1

참가 물질

반응물 2

HCID 128723233-Bromo-6-chloroimidazo(1,2-b)pyridazine

HCID 71491984HCID 71491984, 화합물

생성물 1

HCID 71491985HCID 71491985, 화합물

실험 절차

6-Chloro-3-(furo[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyridazine was prepared in analogy to 6-chloro-3-(furo[3,2-b]pyridin-2-yl)imidazo[1,2-b]pyridazine starting from 314 mg (1.35 mmol) of 3-bromo-6-chloroimidazo[1,2-b]pyridazine to yield 62% of a solid material.

출처 및 근거

ORD 기록: ord-e77e43c136a94741a679ca75b82367fc
출처 데이터셋: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09409889B2

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