참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | tert-Butyl carbamate | HCID 77922 | — |
| 반응물 | 2,6-Dichloroisonicotinic acid | HCID 94830 | — |
| 시약 | Potassium Phosphate, Tribasic | HCID 62657 | — |
| 촉매 | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| 촉매 | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid | HCID 72212052 | 0% |
반응 단계
Reagents were mixed in a 25 mL round bottom flask and flushed well with nitrogen - heated at 100 °C for 16 h. The mixture looked dark black. Could not detect any starting material or product! It was discarded.
출처 및 근거
| 출처 데이터셋 | 750 AstraZeneca ELN dataset |
|---|
| ORD ID | ord-7c9ead47a3324fac997f2b8af6afca02 |
|---|
| 출처 메모 | 750 AstraZeneca ELN dataset |
|---|
