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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1480050생성일: 2026년 10월 26일

(S)-2-amino-2,3-dimethylbutan-1-ol → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-1,2-dimethyl-propyl)-amide

https://huagongshe.com/reaction/1480050

반응식

참여 물질

역할이름HCID투입량
반응물(S)-2-amino-2,3-dimethylbutan-1-olHCID 14919272—
반응물5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203638—
생성물5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-1,2-dimethyl-propyl)-amideHCID 76282000—

반응 단계

The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and (2S)-2-amino-2,3-dimethyl-1-butanol (CAN 7533-40-6) as starting materials and isolated (21 mg, 73%) as colorless oil; MS (ESI, m/z): 327.2 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09409866B2
출처 데이터셋uspto-grants-2016_08
ORD IDord-43712133c7234d2c86c0a9a2a12aecae
출처 메모uspto-grants-2016_08