Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Leucinamide → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Leucinamide | HCID 69640 | — |
| 반응물 | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203809 | — |
| 생성물 | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide | HCID 76282722 | — |
반응 단계
The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and (S)-2-Amino-4-methyl-pentanoic acid amide (CAN 687-51-4) as starting materials and isolated (10.5 mg, 20%) as colorless oil; MS (ESI, m/z): 346.6 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09409866B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-89766d2e680b4c3db89b5bacad8738bb |
| 출처 메모 | uspto-grants-2016_08 |