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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1480112생성일: 2026년 10월 26일

1-(Aminomethyl)cyclopentan-1-ol--hydrogen chloride (1/1) → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-hydroxy-cyclopentylmethyl)-amide

https://huagongshe.com/reaction/1480112

반응식

참여 물질

역할이름HCID투입량
반응물1-(Aminomethyl)cyclopentan-1-ol--hydrogen chloride (1/1)HCID 21109693—
반응물5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203809—
생성물5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-hydroxy-cyclopentylmethyl)-amideHCID 76284221—

반응 단계

The title compound was synthesized in analogy to Example 54, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and 1-(aminomethyl)cyclopentanol hydrochloride (CAN 76066-27-8) as starting materials and isolated (71 mg, 63%) as a white solid; MS (ESI, m/z): 331.0 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09409866B2
출처 데이터셋uspto-grants-2016_08
ORD IDord-a5afc7e1dceb466985df8d139186b165
출처 메모uspto-grants-2016_08