O-Methyltyramine → 1-(3-{2-[2-(4-Methoxy-phenyl)-ethylamino]-pyrimidin-4-yl}-phenyl)-ethanone
반응식
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([C:14](=[O:16])[CH3:15])[CH:11]=[CH:12][CH:13]=2)[CH:5]=[CH:4][N:3]=1.[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][CH2:26][NH2:27])=[CH:21][CH:20]=1>>[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][CH2:26][NH:27][C:2]2[N:7]=[C:6]([C:8]3[CH:9]=[C:10]([C:14](=[O:16])[CH3:15])[CH:11]=[CH:12][CH:13]=3)[CH:5]=[CH:4][N:3]=2)=[CH:21][CH:20]=1참가 물질
3
실험 절차
Intermediate 38 was coupled with 2-(4-Methoxy-phenyl)-ethylamine following procedure F. LC-MS showed the product had the expected M+H+ of 348.
출처 및 근거
- ORD 기록
- ord-f5a63f1faa6d4985a180df4662fae4d8
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07732444B2
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