Thionyl Chloride → HCID 178521140, 화합물

HRID 1480480노트

반응식

HRID 1480480 반응식
[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][CH2:8][C:9]([OH:11])=O)[N:3]=[N:2]1.S(Cl)([Cl:14])=O>C(Cl)Cl>[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][CH2:8][C:9]([Cl:14])=[O:11])[N:3]=[N:2]1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 178525383HCID 178525383, 화합물

생성물 1

HCID 178521140HCID 178521140, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a stirred suspension of 4-(1H-1,2,3-triazol-4-yl)butanoic acid (Example 17, step 4) (0.088 g, 0.57 mmol) in DCM (5 mL) at RT under nitrogen was added thionyl chloride (0.499 mL, 6.84 mmol) and the reaction mixture stirred at RT for 2 hours. The reaction mixture was concentrated under reduced pressure to afford the crude title product.

후처리

  1. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-44dcd45add1445998e76ddb6bf129943
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09409895B2

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