Thionyl Chloride → HCID 178521139, 화합물
반응식
[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][C:8]([OH:10])=O)[N:3]=[N:2]1.S(Cl)([Cl:13])=O>C(Cl)Cl>[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][C:8]([Cl:13])=[O:10])[N:3]=[N:2]1참가 물질
4
실험 절차
To a solution of 3-(1H-1,2,3-triazol-4-yl)propanoic acid (Example 19, step 2) (100 mg, 0.709 mmol) in DCM (5 mL) at RT under nitrogen was added thionyl chloride (0.621 mL, 8.50 mmol) and the reaction mixture stirred for 2 hours. The reaction mixture was concentrated under reduced pressure to afford the title product.
후처리
- concentrationThe reaction mixture was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-a54b04e4bead41eea60d2d15797dc4fb
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09409895B2
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