2,4-Dichloropyrimidine → 2-Chloro-4-(3-isopropoxy-phenyl)-pyrimidine

HRID 14808

반응식

HRID 14808 반응식
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[CH:9]([O:12][C:13]1[CH:14]=[C:15](B(O)O)[CH:16]=[CH:17][CH:18]=1)([CH3:11])[CH3:10]>>[Cl:1][C:2]1[N:7]=[C:6]([C:17]2[CH:16]=[CH:15][CH:14]=[C:13]([O:12][CH:9]([CH3:11])[CH3:10])[CH:18]=2)[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 775312,4-DichloropyrimidineHCID 50839323-Isopropoxybenzeneboronic acid

생성물 1

HCID 249018192-Chloro-4-(3-isopropoxy-phenyl)-pyrimidine

실험 절차

2,4 dichlorpyrimidine was coupled with 3-isopropoxyphenylboronic acid following procedure A. LC-MS showed the product had the expected M+H+ of 249.

출처 및 근거

ORD 기록
ord-031ae896bdfe463c879b9732a9db5aec
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07732444B2

연결된 노트

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