Piperidine → Boc-D-2,4-diaminobutyric acid
반응식
[NH:1]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[C@@H:2]([C:23]([OH:25])=[O:24])[CH2:3][CH2:4][NH:5]C(OCC1C2C(=CC=CC=2)C2C1=CC=CC=2)=O.N1CCCCC1>CN(C=O)C>[NH2:5][CH2:4][CH2:3][C@@H:2]([NH:1][C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[C:23]([OH:25])=[O:24]참가 물질
4
실험 절차
Boc-D-Dab(Fmoc)-OH (206 mg, 0.5 mmol, Oakwood Products) and piperidine (0.3 mL, 3.03 mmol) were dissolved in DMF (1.6 mL). The resulting mixture was stirred at room temperature for 30 minutes. The volatiles were removed in vacuo and the residue was used directly in the subsequent step without further purification.
후처리
- customThe volatiles were removed in vacuo
- customthe residue was used directly in the subsequent step without further purification
출처 및 근거
- ORD 기록
- ord-65e57136971f48aa98e198a154513e6a
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09409892B2
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