2-Chloro-5-methylbenzoic Acid → 2-Chloro-5-methyl-N-(2-morpholin-4-yl-2-pyridin-3-yl-ethyl)-benzamide

HRID 1482501노트

반응식

HRID 1482501 반응식
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[C:4]([OH:6])=O.[N:12]1([CH:18]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)[CH2:19][NH2:20])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[C:4]([NH:20][CH2:19][CH:18]([N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1)=[O:6]

참가 물질

3

반응물 2

HCID 2404302-Chloro-5-methylbenzoic AcidHCID 49889912-Morpholin-4-yl-2-(3-pyridyl)ethylamine

생성물 1

HCID 736734362-Chloro-5-methyl-N-(2-morpholin-4-yl-2-pyridin-3-yl-ethyl)-benzamide

실험 절차

From 2-chloro-5-methylbenzoic acid and (2-morpholin-4-yl-2-pyridin-3-ylethyl)amine. LCMS (MH+): m/z=360.0, tR (minutes, Method A)=0.77

출처 및 근거

ORD 기록
ord-27b8585ef1944922bf2c23328f92b503
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09415055B2

반응 노트

불러오는 중…