HCID 90134933, 화합물 → HCID 69288665, 화합물

HRID 1483038노트

반응식

HRID 1483038 반응식
[N:1]([CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7](=[O:15])[NH:6]1)=[N+]=[N-]>CCOC(C)=O.[Pd]>[NH2:1][CH2:4][CH:5]1[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7](=[O:15])[NH:6]1

참가 물질

4

반응물 1

HCID 90134933HCID 90134933, 화합물

생성물 1

HCID 69288665HCID 69288665, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

Dissolve 3-(azidomethyl)-3,4-dihydro-2H-isoquinolin-1-one (1.8 g, 8.9 mmol) in EtOAc (15 mL). Under a nitrogen atmosphere add 10% Pd/C (0.2 g) then stir overnight under a hydrogen atmosphere. Filter reaction mixture through Celite® and wash the Celite® with EtOAc. MS (m/z): 177 (M+1).

후처리

  1. filtrationFilter
  2. customreaction mixture through Celite®
  3. washwash the Celite® with EtOAc

출처 및 근거

ORD 기록
ord-993a92fe52f4474ab7dbf242ac845114
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09416138B2

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