5-(trifluoromethyl)pyridine-2-carboxylic Acid → N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(trifluoromethyl)pyridine-2-carboxamide

HRID 148313

반응식

HRID 148313 반응식
[F:21][C:22]([c:23]1[cH:24][cH:25][c:26]([C:29](=[O:30])[OH:31])[n:27][cH:28]1)([F:32])[F:33].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1)[C:29]([c:26]1[cH:25][cH:24][c:23]([C:22]([F:21])([F:32])[F:33])[cH:28][n:27]1)=[O:30]

참가 물질

3

반응물 2

HCID 109103495-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 672341894-(5-Amino-2-fluorophenyl)-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-2-amine

생성물 1

HCID 75986855N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(trifluoromethyl)pyridine-2-carboxamide

출처 및 근거

ORD 기록
ord-162f7af44cd94e278a032d05b85957c2
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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