4-Fluorophenol → 5-(2-(4-Fluorophenoxy)-4-(perfluoroethyl)benzamido)picolinic acid

반응식

[F:1][C:2]1[CH:33]=[CH:32][C:5]([O:6][C:7]2[CH:24]=[C:23]([C:25]([F:31])([F:30])[C:26]([F:29])([F:28])[F:27])[CH:22]=[CH:21][C:8]=2[C:9]([NH:11][C:12]2[CH:13]=[CH:14][C:15]([C:18]([OH:20])=[O:19])=[N:16][CH:17]=2)=[O:10])=[C:4](OC)[CH:3]=1.FC1C=CC(O)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][C:7]2[CH:24]=[C:23]([C:25]([F:31])([F:30])[C:26]([F:27])([F:29])[F:28])[CH:22]=[CH:21][C:8]=2[C:9]([NH:11][C:12]2[CH:13]=[CH:14][C:15]([C:18]([OH:20])=[O:19])=[N:16][CH:17]=2)=[O:10])=[CH:32][CH:33]=1

참가 물질

반응물 2

HCID 97324-Fluorophenol

HCID 778456115-(2-(4-fluoro-2-methoxyphenoxy)-4-(perfluoroethyl)benzamido)picolinic Acid

생성물 1

HCID 778456105-(2-(4-Fluorophenoxy)-4-(perfluoroethyl)benzamido)picolinic acid

실험 절차

5-(2-(4-Fluorophenoxy)-4-(perfluoroethyl)benzamido)picolinic acid (73) was prepared as described above for compound 72 from 4-fluorophenol.

출처 및 근거

ORD 기록: ord-7e2d77dfdd7241509b634bf6f91d8bf6
출처 데이터셋: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09421196B2

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