Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-dimethyl-4-nitrobenzenesulfonamide → Benzenesulfonamide, 4-amino-N,N-dimethyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-dimethyl-4-nitrobenzenesulfonamide | HCID 2747580 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Benzenesulfonamide, 4-amino-N,N-dimethyl- | HCID 74369 | 95% |
반응 단계
Under H2, N,N-dimethyl-4-nitrobenzenesulfonamide (879 mg, 3.8 mmol, 1.0 equiv.) was catalytically hydrogenated in the presence of Pd/C (40 mg) in MeOH (25 mL). When no more H2 was consumed, the reaction mixture was filtered. The filtrate was concentrated and crystallized to afford compound 4-amino-N,N-dimethyl benzenesulfonamide (722 mg, 95%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09422271B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-516b0c9b1bff4851872f7983c660b89c |
| 출처 메모 | uspto-grants-2016_08 |