Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitromethane → 2-Fluoro-1-methoxy-4-(2-nitro-vinyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitromethane | HCID 6375 | — |
| 반응물 | 3-Fluoro-p-anisaldehyde | HCID 67696 | — |
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 생성물 | 2-Fluoro-1-methoxy-4-(2-nitro-vinyl)benzene | HCID 53414639 | — |
반응 단계
3-Fluoro-4-methoxy-benzaldehyde (10 g) was dissolved in 100 mL of nitromethane along with 5 g of ammonium acetate. The mixture was refluxed for 2 hours. The nitromethane was removed by rotary evaporation and the residue recrystallized from ethanol to give 7.6 g of the expected product. LC-MS showed the product had the expected M+H+ of 198.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732444B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-9fee8e75ba3d4258a595d0347fb4ef58 |
| 출처 메모 | uspto-grants-2010_06 |