(2S)-2-amino-2-cyclopentylacetic acid → (S)-2-Cyclopentyl-2-((methoxycarbonyl)amino)acetic acid

반응식

[CH3:1][O:2][C:3]([NH:5][C@H:6]([C:10]([OH:12])=[O:11])[CH:7]([CH3:9])[CH3:8])=[O:4].N[C@@H:14](C1CCCC1)[C:15](O)=O>>[CH:7]1([C@H:6]([NH:5][C:3]([O:2][CH3:1])=[O:4])[C:10]([OH:12])=[O:11])[CH2:9][CH2:15][CH2:14][CH2:8]1

참가 물질

반응물 2

HCID 10374564(2S)-2-amino-2-cyclopentylacetic acid

HCID 10942966(2S)-2-((methoxycarbonyl)amino)-3-methylbutanoic acid

생성물 1

HCID 66630234(S)-2-Cyclopentyl-2-((methoxycarbonyl)amino)acetic acid

실험 절차

(S)-2-cyclopentyl-2-(methoxycarbonylamino)acetic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using (S)-2-amino-2-cyclopentylacetic acid instead of L-Valine.

출처 및 근거

ORD 기록: ord-cdf17261db1142c9a4cb794e73bdfdb7
출처 데이터셋: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09427428B2

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