5-Bromo-3-pyridinecarboxaldehyde → 1-(5-Bromo-pyridin-3-ylmethyl)-piperidine-4-carboxylic acid cyclohexylamide

HRID 1486735노트

반응식

HRID 1486735 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=O)[CH:5]=[N:6][CH:7]=1.Cl.[CH:11]1([NH:17][C:18]([CH:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)=[O:19])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([NH:17][C:18]([CH:20]2[CH2:21][CH2:22][N:23]([CH2:8][C:4]3[CH:5]=[N:6][CH:7]=[C:2]([Br:1])[CH:3]=3)[CH2:24][CH2:25]2)=[O:19])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

참가 물질

3

반응물 2

HCID 27847345-Bromo-3-pyridinecarboxaldehydeHCID 44630870N-cyclohexylpiperidine-4-carboxamide hydrochloride

생성물 1

HCID 867065531-(5-Bromo-pyridin-3-ylmethyl)-piperidine-4-carboxylic acid cyclohexylamide

실험 절차

The title compound is prepared according to the reaction 3.01c described above using 5-bromo-pyridine-3-carboxaldehyde and piperidine-4-carboxylic acid cyclohexylamide hydrochloride as in 3.01c: LC-MS A: tR=0.58 min; [M+H]+=380.19.

출처 및 근거

ORD 기록
ord-83b8cc9d597e4c6bb80274f9d35de46d
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09428456B2

반응 노트

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