Methanol → tert-butyl N-(4-bromo-2-fluorophenyl)-N-[6-chloro-5-(2-hydroxyethyl)pyrimidin-4-yl]carbamate

HRID 148719노트

반응식

[BH4-:27].[Br:1][c:2]1[cH:3][c:4]([F:26])[c:5]([N:8]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[c:16]2[n:17][cH:18][n:19][c:20]([Cl:25])[c:21]2[CH2:22][CH:23]=[CH2:24])[cH:6][cH:7]1.[CH3:29][OH:30].[Cl:31][CH2:32][Cl:33].[Na+:28]>>[Br:1][c:2]1[cH:3][c:4]([F:26])[c:5]([N:8]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[c:16]2[n:17][cH:18][n:19][c:20]([Cl:25])[c:21]2[CH2:22][CH2:23][OH:30])[cH:6][cH:7]1